New Willsey Lab study investigates the shared biological underpinnings of autism and congenital heart disease

In collaboration with Trey Ideker’s lab at UCSD and Mustafa Khokha’s lab at Yale, we used network genetics to identify a convergent molecular network underlying autism and congenital heart disease, two co-morbid disorders with shared genetic risk. This network is impacted by damaging genetic variants from both disorders in multiple independent cohorts of patients, pinpointing […]

Congratulations to Nia for winning Autism Speaks Fellowship

Autism Speaks, the global nonprofit dedicated to promoting solutions, across the spectrum and throughout the life span, for the needs of people with autism and their families, today announced more than $4.7 million in grant funding to 26 researchers studying autism. As a major funder of autism research, Autism Speaks is committed to advancing the […]

The Psychiatric Cell Map Initiative

A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders Although gene discovery in neuropsychiatric disorders, including autism spectrum disorder, intellectual disability, epilepsy, schizophrenia, and Tourette disorder, has accelerated, resulting in a large number of molecular clues, it has proven difficult to generate specific hypotheses without the corresponding datasets at the protein […]

Willsey Lab’s work on genetic risk factors for Tourette disorder hailed as one of Neuron’s top papers for 2016-2017

The work of a multi-institution research team led in part by UCSF Department of Psychiatry scientists Jeremy Willsey, Stephan Sanders, and Matthew State has been recognized by Neuron with inclusion on the journal’s “Best of 2016-2017” list. Their paper, “De Novo Coding Variants Are Strongly Associated With Tourette Disorder,” was cited as one of the five most accessed research […]

Dr. Willsey receives UCSF Weill Institute for Neurosciences Trailblazer Award

Jeremy Willsey, PhD, will map the core molecular networks underlying autism. This will provide critical insights into pathology and treatment to generate a new paradigm for investigating neuropsychiatric disorders that bridges the current gap between genetics and functional biology.