In collaboration with Trey Ideker’s lab at UCSD and Mustafa Khokha’s lab at Yale, we used network genetics to identify a convergent molecular network underlying autism and congenital heart disease, two co-morbid disorders with shared genetic risk. This network is impacted by damaging genetic variants from both disorders in multiple independent cohorts of patients, pinpointing […]
The NIMH Outstanding Resident Award Program (ORAP) was introduced to the psychiatry residency training community over 30 years ago to recognize residents with outstanding research and academic potential. The NIMH Intramural Research Program (IRP) has sponsored ORAP since its inception in 1988. Belinda was one of 12 recipients of this award for 2020.
Autism Speaks, the global nonprofit dedicated to promoting solutions, across the spectrum and throughout the life span, for the needs of people with autism and their families, today announced more than $4.7 million in grant funding to 26 researchers studying autism. As a major funder of autism research, Autism Speaks is committed to advancing the […]
The UCSF Quantitative Biosciences Institute, in collaboration with the Department of Psychiatry, and the Department of Radiology, launched a 900K RFA aimed to more effectively connect the basic and clinical research programs at UCSF through two funding mechanisms, BOLD & BASIC GRANTS and FELLOWSHIPS. Among 2019’s grant winners were the Willsey Lab’s Nawei Sun and […]
In the largest DNA sequencing study of Tourette Disorder (TD) to date, UC San Francisco researchers and their collaborators have unearthed new data suggesting a potential role for disruptions in cell polarity in the development of this condition. In their new study, published online September 25, 2018 in Cell Reports the researchers focused on “de novo” […]
Psychiatric Cell Mapping Initiative Will Focus First on Autism, Taking Advantage of the Many Genes Implicated in the Disorder. The PCMI was founded by the UCSF Quantitative Biosciences Institute (QBI) in collaboration with the Department of Psychiatry. Founding faculty include QBI Director Nevan Krogan, PhD, a professor of Cellular and Molecular Pharmacology at UCSF and […]
A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders Although gene discovery in neuropsychiatric disorders, including autism spectrum disorder, intellectual disability, epilepsy, schizophrenia, and Tourette disorder, has accelerated, resulting in a large number of molecular clues, it has proven difficult to generate specific hypotheses without the corresponding datasets at the protein […]
The work of a multi-institution research team led in part by UCSF Department of Psychiatry scientists Jeremy Willsey, Stephan Sanders, and Matthew State has been recognized by Neuron with inclusion on the journal’s “Best of 2016-2017” list. Their paper, “De Novo Coding Variants Are Strongly Associated With Tourette Disorder,” was cited as one of the five most accessed research […]
Our recent publication on de novo variants and Tourette disorder has been named one of the top five articles in Neuron for 2016-17. Excited to be recognized by this great journal! http://info.cell.com/best-of-neuron-2016-2017
Jeremy Willsey, PhD, will map the core molecular networks underlying autism. This will provide critical insights into pathology and treatment to generate a new paradigm for investigating neuropsychiatric disorders that bridges the current gap between genetics and functional biology. http://weill.ucsf.edu/news/ucsf-weill-institute-neurosciences-announces-trailblazer-awards
