In the largest DNA sequencing study of Tourette Disorder (TD) to date, UC San Francisco researchers and their collaborators have unearthed new data suggesting a potential role for disruptions in cell polarity in the development of this condition. In their new study, published online September 25, 2018 in Cell Reports the researchers focused on “de novo” […]
Psychiatric Cell Mapping Initiative Will Focus First on Autism, Taking Advantage of the Many Genes Implicated in the Disorder. The PCMI was founded by the UCSF Quantitative Biosciences Institute (QBI) in collaboration with the Department of Psychiatry. Founding faculty include QBI Director Nevan Krogan, PhD, a professor of Cellular and Molecular Pharmacology at UCSF and […]
A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders Although gene discovery in neuropsychiatric disorders, including autism spectrum disorder, intellectual disability, epilepsy, schizophrenia, and Tourette disorder, has accelerated, resulting in a large number of molecular clues, it has proven difficult to generate specific hypotheses without the corresponding datasets at the protein […]
The work of a multi-institution research team led in part by UCSF Department of Psychiatry scientists Jeremy Willsey, Stephan Sanders, and Matthew State has been recognized by Neuron with inclusion on the journal’s “Best of 2016-2017” list. Their paper, “De Novo Coding Variants Are Strongly Associated With Tourette Disorder,” was cited as one of the five most accessed research […]
Our recent publication on de novo variants and Tourette disorder has been named one of the top five articles in Neuron for 2016-17. Excited to be recognized by this great journal! http://info.cell.com/best-of-neuron-2016-2017
Jeremy Willsey, PhD, will map the core molecular networks underlying autism. This will provide critical insights into pathology and treatment to generate a new paradigm for investigating neuropsychiatric disorders that bridges the current gap between genetics and functional biology. http://weill.ucsf.edu/news/ucsf-weill-institute-neurosciences-announces-trailblazer-awards
